The Institute for Global Health and Health Policy (IGHHP) is a U.S. registered 501(c)(3) non-profit organization comprised of programmatic initiatives whose core mission is to promote education, research, outreach and policy in the service of One Health – a discipline that explores the connections between human, animal and ecosystem health by examining the root causes of contemporary declines in planetary wellness. Training workshops currently focus on veterinary and ecology students, with a goal of involving other professional study areas such as medicine, public health, agriculture, public policy, socioeconomics, education, business, ecological economics, agricultural economics and cultural anthropology – all of which are relevant to the complexities of wellness problem-solving in the global context. The overarching mission of IGHHP is, therefore, to adopt a broad-based, interdisciplinary, systems approach to population and environmental health education, research, community outreach and social policy that seeks early remedial intervention upstream in the runway cascade of health dysfunction. The goal is to identify One Health concepts that are actionable on a global scale, but whose specifics are developed as “grassroots” strategies at the local level by impacted communities.